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Chemoinformatics and Bioinformatics in the Pharmaceutical Sciences
brings together two very important fields in pharmaceutical
sciences that have been mostly seen as diverging from each other:
chemoinformatics and bioinformatics. As developing drugs is an
expensive and lengthy process, technology can improve the cost,
efficiency and speed at which new drugs can be discovered and
tested. This book presents some of the growing advancements of
technology in the field of drug development and how the
computational approaches explained here can reduce the financial
and experimental burden of the drug discovery process. This book
will be useful to pharmaceutical science researchers and students
who need basic knowledge of computational techniques relevant to
their projects. Bioscientists, bioinformaticians, computational
scientists, and other stakeholders from industry and academia will
also find this book helpful.
Fiber and Textile Engineering in Drug Delivery Systems explains how
innovative textile processing methods including rotary spinning,
microfluidics, wet spinning and electrospinning can be used to
produce novel drug delivery solutions. This topical book provides
detailed descriptions of how to produce such new materials for this
purpose, with foundational content to help readers from a range of
backgrounds understand the context of material selection and design
decisions. Emphasis is given to the engineering side of the
manufacturing of the textile and its role in drug delivery, but
this also acts as a guide to pharmaceutical applications of textile
fibers for materials scientists. Drug delivery research is rapidly
expanding and experimenting with new materials to drive improved
clinical outcomes as the efficacy of the therapeutic molecule is
highly dependent on the right choice of carrier system. Recently,
fiber based carriers at both nano and micro scales are gaining
interest in the scientific community due to ease of manufacturing,
high surface area to volume ratio, desirable drug release kinetics
and high mechanical strength.
Computational Biology for Stem Cell Research is an invaluable guide
for researchers as they explore HSCs and MSCs in computational
biology. With the growing advancement of technology in the field of
biomedical sciences, computational approaches have reduced the
financial and experimental burden of the experimental process. In
the shortest span, it has established itself as an integral
component of any biological research activity. HSC informatics (in
silico) techniques such as machine learning, genome network
analysis, data mining, complex genome structures, docking, system
biology, mathematical modeling, programming (R, Python, Perl, etc.)
help to analyze, visualize, network constructions, and
protein-ligand or protein-protein interactions. This book is aimed
at beginners with an exact correlation between the biomedical
sciences and in silico computational methods for HSCs
transplantation and translational research and provides insights
into methods targeting HSCs properties like proliferation,
self-renewal, differentiation, and apoptosis.
The goal of modern dentistry is to restore the patient to normal
contour, function, comfort esthetics and health. The implant
dentistry has unique ability to achieve this goal as it offers the
increased function, improved strength, Bone preservation and better
pschycological results as compared to conventional complete
dentures. The placement of implants should not be undertaken
without careful consideration of many variables, including systemic
and local host factors and the design of the prosthesis. The
ability to reliably identify patients and conditions with greater
potential for failure would be valuable. Hence, treatment planning
for the placement and restoration of Osseo integrated dental
implant involves the consideration of many variables, including
systemic and local host factors and the design of the prosthesis.
With appropriate diagnosis and conscientious treatment planning,
the use of endosseous oral implants enjoys good prognosis.
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